MAP2 Protein (AA 2-478) (His tag)

N° du produit ABIN5713640

Détail du produit

Antigène: MAP2 (Microtubule-Associated Protein 2 (MAP2))

Type de proteíne: Recombinant

Attributs du protein: AA 2-478

Origine: Humain

Source: Levure

Purification/Conjugué: Cette MAP2 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: AGVEEVAASG SHLNGDLDPD DREEGAASTA EEAAKKKRRK KKKSKGPSAA GEQEPDKESG ASVDEVARQL ERSALEDKER DEDDEDGDGD GDGATGKKKK KKKKKRGPKV QTDPPSVPIC DLYPNGVFPK GQECEYPPTQ DGRTAAWRTT SEEKKALDQA SEEIWNDFRE AAEAHRQVRK YVMSWIKPGM TMIEICEKLE DCSRKLIKEN GLNAGLAFPT GCSLNNCAAH YTPNAGDTTV LQYDDICKID FGTHISGRII DCAFTVTFNP KYDTLLKAVK DATNTGIKCA GIDVRLCDVG EAIQEVMESY EVEIDGKTYQ VKPIRNLNGH SIGQYRIHAG KTVPIVKGGE ATRMEEGEVY AIETFGSTGK GVVHDDMECS HYMKNFDVGH VPIRLPRTKH LLNVINENFG TLAFCRRWLD RLGESKYLMA LKNLCDLGIV DPYPPLCDIK GSYTAQFEHT ILLRPTCKEV VSRGDDY

Purification: SDS-PAGE

Pureté: > 90 %

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Stock: -80 °C,4 °C,-20 °C

Stockage commentaire: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Détail du antigène

Antigène: MAP2 (Microtubule-Associated Protein 2 (MAP2))

Autre désignation: MAP2 (MAP2 Produits)

Synonymes: MAP2A Protein, MAP2B Protein, MAP2C Protein, MAP2R Protein, Mtap2 Protein, MAP-2 Protein, Mtap-2 Protein, xmap2 Protein, MGC53131 Protein, a730034c02 Protein, zgc:103474 Protein, zgc:113974 Protein, microtubule associated protein 2 Protein, microtubule-associated protein 2 Protein, microtubule associated protein 2 S homeolog Protein, MAP2 Protein, Map2 Protein, map2.S Protein, map2 Protein

Sujet: Cotranslationally roves the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). The catalytic activity of human METAP2 toward Met-Val peptides is consistently two orders of magnitude higher than that of METAP1, suggesting that it is responsible for processing proteins containing N-terminal Met-Val and Met-Thr sequences in vivo.Protects eukaryotic initiation factor EIF2S1 from translation-inhibiting phosphorylation by inhibitory kinases such as EIF2AK2/PKR and EIF2AK1/HCR. Plays a critical role in the regulation of protein synthesis.

Poids moléculaire: 54.7 kDa

UniProt: P50579