DIO3 Protein (AA 37-278, Extracellular) (His tag)
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- Antigène Voir toutes DIO3 Protéines
- DIO3 (Deiodinase, Iodothyronine, Type III (DIO3))
- Type de proteíne
- Recombinant
- Attributs du protein
- Extracellular, AA 37-278
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Origine
- Rat
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Source
- Levure
- Purification/Conjugué
- Cette DIO3 protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Séquence
- DFLCIRKHFL RRRHPDHPEP EVELNSEGEE MPPDDPPICV SDDNRLCTLA SLKAVWHGQK LDFFKQAHEG GPAPNSEVVR PDGFQSQRIL DYAQGTRPLV LNFGSCTPPF MARMSAFQRL VTKYQRDVDF LIIYIEEAHP SDGWVTTDSP YVIPQHRSLE DRVSAARVLQ QGAPGCALVL DTMANSSSSA YGAYFERLYV IQSGTIMYQG GRGPDGYQVS ELRTWLERYD EQLHGTRPRR L
- Purification
- SDS-PAGE
- Pureté
- > 90 %
- Top Product
- Discover our top product DIO3 Protéine
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Stock
- -80 °C,4 °C,-20 °C
- Stockage commentaire
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Antigène
- DIO3 (Deiodinase, Iodothyronine, Type III (DIO3))
- Autre désignation
- IOD3 (DIO3 Produits)
- Synonymes
- 5DIII Protein, DIOIII Protein, txdi3 Protein, dioiii Protein, XL-15 Protein, itdi3 Protein, D3 Protein, TXDI3 Protein, iodothyronine deiodinase 3 Protein, deiodinase, iodothyronine, type 3 Protein, deiodinase, iodothyronine, type III Protein, deiodinase, iodothyronine type III Protein, deiodinase, iodothyronine, type 3 L homeolog Protein, DIO3 Protein, dio3 Protein, Dio3 Protein, dio3.L Protein
- Sujet
- Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into RT3 (3,3',5'-triiodothyronine) and of T3 (3,5,3'-triiodothyronine) into T2 (3,3'-diiodothyronine). RT3 and T2 are inactive metabolites. May play a role in preventing prature exposure of developing fetal tissues to adult levels of thyroid hormones. Can regulate circulating fetal thyroid hormone concentrations throughout gestation. Essential role for regulation of thyroid hormone inactivation during bryological development.
- Poids moléculaire
- 29.4 kDa
- UniProt
- P49897
- Pathways
- Hormone Activity
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