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DIO3 Protein (AA 37-278, Extracellular) (His tag)

DIO3 Origine: Rat Hôte: Levure Recombinant > 90 % SDS
N° du produit ABIN5714130
  • Antigène Voir toutes DIO3 Protéines
    DIO3 (Deiodinase, Iodothyronine, Type III (DIO3))
    Type de proteíne
    Recombinant
    Attributs du protein
    Extracellular, AA 37-278
    Origine
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Rat
    Source
    • 7
    • 6
    • 2
    • 2
    Levure
    Purification/Conjugué
    Cette DIO3 protéine est marqué à la His tag.
    Application
    SDS-PAGE (SDS)
    Séquence
    DFLCIRKHFL RRRHPDHPEP EVELNSEGEE MPPDDPPICV SDDNRLCTLA SLKAVWHGQK LDFFKQAHEG GPAPNSEVVR PDGFQSQRIL DYAQGTRPLV LNFGSCTPPF MARMSAFQRL VTKYQRDVDF LIIYIEEAHP SDGWVTTDSP YVIPQHRSLE DRVSAARVLQ QGAPGCALVL DTMANSSSSA YGAYFERLYV IQSGTIMYQG GRGPDGYQVS ELRTWLERYD EQLHGTRPRR L
    Purification
    SDS-PAGE
    Pureté
    > 90 %
    Top Product
    Discover our top product DIO3 Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Stock
    -80 °C,4 °C,-20 °C
    Stockage commentaire
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Antigène
    DIO3 (Deiodinase, Iodothyronine, Type III (DIO3))
    Autre désignation
    IOD3 (DIO3 Produits)
    Synonymes
    5DIII Protein, DIOIII Protein, txdi3 Protein, dioiii Protein, XL-15 Protein, itdi3 Protein, D3 Protein, TXDI3 Protein, iodothyronine deiodinase 3 Protein, deiodinase, iodothyronine, type 3 Protein, deiodinase, iodothyronine, type III Protein, deiodinase, iodothyronine type III Protein, deiodinase, iodothyronine, type 3 L homeolog Protein, DIO3 Protein, dio3 Protein, Dio3 Protein, dio3.L Protein
    Sujet
    Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into RT3 (3,3',5'-triiodothyronine) and of T3 (3,5,3'-triiodothyronine) into T2 (3,3'-diiodothyronine). RT3 and T2 are inactive metabolites. May play a role in preventing prature exposure of developing fetal tissues to adult levels of thyroid hormones. Can regulate circulating fetal thyroid hormone concentrations throughout gestation. Essential role for regulation of thyroid hormone inactivation during bryological development.
    Poids moléculaire
    29.4 kDa
    UniProt
    P49897
    Pathways
    Hormone Activity
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