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CD163 Protein (CD163) (AA 86-365, partial) (His tag)

CD163 Origine: Souris Hôte: Levure Recombinant > 90 % SDS
N° du produit ABIN5714360
  • Antigène Voir toutes CD163 Protéines
    CD163
    Type de proteíne
    Recombinant
    Attributs du protein
    partial, AA 86-365
    Origine
    • 13
    • 6
    • 2
    • 1
    Souris
    Source
    • 9
    • 6
    • 4
    • 1
    • 1
    Levure
    Purification/Conjugué
    Cette CD163 protéine est marqué à la His tag.
    Application
    SDS-PAGE (SDS)
    Séquence
    VVCQQLGCPT SIKALGWANS SAGSGYIWMD KVSCTGNESA LWDCKHDGWG KHNCTHEKDA GVTCSDGSNL EMRLVNSAGH RCLGRVEIKF QGKWGTVCDD NFSKDHASVI CKQLGCGSAI SFSGSAKLGA GSGPIWLDDL ACNGNESALW DCKHRGWGKH NCDHAEDVGV ICLEGADLSL RLVDGVSRCS GRLEVRFQGE WGTVCDDNWD LRDASVVCKQ LGCPTAISAI GRVNASEGSG QIWLDNISCE GHEATLWECK HQEWGKHYCH HREDAGVTCS
    Purification
    SDS-PAGE
    Pureté
    > 90 %
    Top Product
    Discover our top product CD163 Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Stock
    -80 °C,4 °C,-20 °C
    Stockage commentaire
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Antigène
    CD163
    Autre désignation
    C163A (CD163 Produits)
    Synonymes
    DMBT1 Protein, CD163 Protein, CD163v2 Protein, CD163v3 Protein, M130 Protein, MM130 Protein, deleted in malignant brain tumors 1 protein-like Protein, CD163 molecule Protein, CD163 antigen Protein, LOC426820 Protein, CD163 Protein, Cd163 Protein
    Sujet
    Involved in clearance and endocytosis of hoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hoglobin/haptoglobin and subsequent breakdown of he. Binds hoglobin/haptoglobin complexes in a calcium-dependent and pH -dependent manner. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1 .After shedding, the soluble form (sCD163) may play an anti-inflammatory role.
    Poids moléculaire
    32.2 kDa
    UniProt
    Q2VLH6
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