ATG16L1 Protein (AA 1-607, full length) (His tag)

N° du produit ABIN5714382

Détail du produit

Antigène: ATG16L1 (ATG16 Autophagy Related 16-Like 1 (ATG16L1))

Type de proteíne: Recombinant

Attributs du protein: full length, AA 1-607

Origine: Humain

Source: Levure

Purification/Conjugué: Cette ATG16L1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MSSGLRAADF PRWKRHISEQ LRRRDRLQRQ AFEEIILQYN KLLEKSDLHS VLAQKLQAEK HDVPNRHEIS PGHDGTWNDN QLQEMAQLRI KHQEELTELH KKRGELAQLV IDLNNQMQRK DREMQMNEAK IAECLQTISD LETECLDLRT KLCDLERANQ TLKDEYDALQ ITFTALEGKL RKTTEENQEL VTRWMAEKAQ EANRLNAENE KDSRRRQARL QKELAEAAKE PLPVEQDDDI EVIVDETSDH TEETSPVRAI SRAATKRLSQ PAGGLLDSIT NIFGRRSVSS FPVPQDNVDT HPGSGKEVRV PATALCVFDA HDGEVNAVQF SPGSRLLATG GMDRRVKLWE VFGEKCEFKG SLSGSNAGIT SIEFDSAGSY LLAASNDFAS RIWTVDDYRL RHTLTGHSGK VLSAKFLLDN ARIVSGSHDR TLKLWDLRSK VCIKTVFAGS SCNDIVCTEQ CVMSGHFDKK IRFWDIRSES IVREMELLGK ITALDLNPER TELLSCSRDD LLKVIDLRTN AIKQTFSAPG FKCGSDWTRV VFSPDGSYVA AGSAEGSLYI WSVLTGKVEK VLSKQHSSSI NAVAWSPSGS HVVSVDKGCK AVLWAQY

Purification: SDS-PAGE

Pureté: > 90 %

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Stock: -80 °C,4 °C,-20 °C

Stockage commentaire: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Détail du antigène

Antigène: ATG16L1 (ATG16 Autophagy Related 16-Like 1 (ATG16L1))

Autre désignation: A16L1 (ATG16L1 Produits)

Synonymes: APG16L Protein, ATG16A Protein, ATG16L Protein, IBD10 Protein, WDR30 Protein, 1500009K01Rik Protein, Apg16l Protein, Atg16l Protein, Wdr30 Protein, atg16 Protein, atg16l Protein, fb57e05 Protein, wu:fb57e05 Protein, zgc:110147 Protein, autophagy related 16 like 1 Protein, autophagy related 16-like 1 (S. cerevisiae) Protein, autophagy related 16-like 1 Protein, autophagy related 16 like 1 S homeolog Protein, ATG16 autophagy related 16-like 1 (S. cerevisiae) Protein, ATG16L1 Protein, Atg16l1 Protein, atg16l1 Protein, atg16l1.S Protein

Sujet: Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a mbrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal mbrane.

Poids moléculaire: 70.27 kDa

UniProt: Q676U5

Pathways: Autophagy