GREM2 Protein (AA 22-168) (His tag)

N° du produit ABIN5852925

Détail du produit

Antigène: GREM2 (Gremlin 2 (GREM2))

Type de proteíne: Recombinant

Attributs du protein: AA 22-168

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette GREM2 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSRKNRPAG AIPSPYKDGS SNNSERWQHQ IKEVLASSQE ALVVTERKYL KSDWCKTQPL RQTVSEEGCR SRTILNRFCY GQCNSFYIPR HVKKEEESFQ SCAFCKPQRV TSVLVELECP GLDPPFRLKK IQKVKQCRCM SVNLSDSDKQ

Pureté: > 85 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Denatured

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.4M urea, 10 % glycerol

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: GREM2 (Gremlin 2 (GREM2))

Autre désignation: GREM2 (GREM2 Produits)

Synonymes: prdc Protein, zgc:112207 Protein, RGD1560008 Protein, Gremlin2 Protein, Prdc Protein, CKTSF1B2 Protein, DAND3 Protein, PRDC Protein, gremlin 2, DAN family BMP antagonist Protein, gremlin 2, DAN family BMP antagonist b Protein, gremlin 2, cysteine knot superfamily Protein, GREM2 Protein, grem2b Protein, grem2 Protein, Grem2 Protein

Sujet: GREM2 is a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this protein belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this protein may play a role in regulating organogenesis, body patterning, and tissue differentiation. Recombinant human GREM2 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Poids moléculaire: 19 kDa (170aa)

NCBI Accession: NP_071914

UniProt: Q9H772