C1D Protein (AA 1-141) (His tag)

N° du produit ABIN5853022

Détail du produit

Antigène: C1D (C1D Nuclear Receptor Corepressor (C1D))

Type de proteíne: Recombinant

Attributs du protein: AA 1-141

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette C1D protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSMAGEEIN EDYPVEIHEY LSAFENSIGA VDEMLKTMMS VSRNELLQKL DPLEQAKVDL VSAYTLNSMF WVYLATQGVN PKEHPVKQEL ERIRVYMNRV KEITDKKKAG KLDRGAASRF VKNALWEPKS KNASKVANKG KSKS

Pureté: > 85 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.2M NaCl, 50 % glycerol, 2  mM DTT

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: C1D (C1D Nuclear Receptor Corepressor (C1D))

Autre désignation: C1D (C1D Produits)

Synonymes: LRP1 Protein, SUN-CoR Protein, SUNCOR Protein, hC1D Protein, 1110036E10Rik Protein, AI875855 Protein, zgc:103509 Protein, RGD1560600 Protein, C1D nuclear receptor corepressor Protein, C1D nuclear receptor corepressor L homeolog Protein, C1D nuclear receptor co-repressor Protein, C1D Protein, c1d Protein, c1d.L Protein, C1d Protein

Sujet: Nuclear nucleic acid-binding protein C1D, also known as C1D, plays a role in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA, this function may include MPHOSPH6. This protein can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. This protein can induce apoptosis in a p53/TP53 dependent manner. Recombinant human C1D protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 18.4kDa (164aa), confirmed by MALDI-TOF

NCBI Accession: NP_775269

UniProt: Q13901