TEN1 Protein (AA 1-123) (His tag)

N° du produit ABIN7280306

Détail du produit

Antigène: TEN1 (TEN1 Telomerase Capping Complex Subunit (TEN1))

Type de proteíne: Recombinant

Attributs du protein: AA 1-123

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette TEN1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSMMLPKPG TYYLPWEVSA GQVPDGSTLR TFGRLCLYDM IQSRVTLMAQ HGSDQHQVLV CTKLVEPFHA QVGSLYIVLG ELQHQQDRGS VVKARVLTCV EGMNLPLLEQ AIREQRLYKQ ERGGSQ

Pureté: > 90 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 7.5) containing 0.15M NaCl, 10 % glycerol, 1  mM DTT

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: TEN1 (TEN1 Telomerase Capping Complex Subunit (TEN1))

Autre désignation: TEN1 (TEN1 Produits)

Synonymes: C17orf106 Protein, 2310004N24Rik Protein, TEN1, CST complex subunit Protein, TEN1 telomerase capping complex subunit Protein, TEN1 Protein, Ten1 Protein

Sujet: TEN1 is component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites. Recombinant human TEN1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 16.2kDa (146aa), confirmed by MALDI-TOF

NCBI Accession: NP_001106795

UniProt: Q86WV5