NCK2 Protein (AA 1-380) (His tag)

N° du produit ABIN5853122

Détail du produit

Antigène: NCK2 (NCK Adaptor Protein 2 (NCK2))

Type de proteíne: Recombinant

Attributs du protein: AA 1-380

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette NCK2 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSMTEEVIV IAKWDYTAQQ DQELDIKKNE RLWLLDDSKT WWRVRNAANR TGYVPSNYVE RKNSLKKGSL VKNLKDTLGL GKTRRKTSAR DASPTPSTDA EYPANGSGAD RIYDLNIPAF VKFAYVAERE DELSLVKGSR VTVMEKCSDG WWRGSYNGQI GWFPSNYVLE EVDEAAAESP SFLSLRKGAS LSNGQGSRVL HVVQTLYPFS SVTEEELNFE KGETMEVIEK PENDPEWWKC KNARGQVGLV PKNYVVVLSD GPALHPAHAP QISYTGPSSS GRFAGREWYY GNVTRHQAEC ALNERGVEGD FLIRDSESSP SDFSVSLKAS GKNKHFKVQL VDNVYCIGQR RFHTMDELVE HYKKAPIFTS EHGEKLYLVR ALQ

Pureté: > 85 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.15M NaCl, 30 % glycerol, 1  mM DTT

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: NCK2 (NCK Adaptor Protein 2 (NCK2))

Autre désignation: NCK2 (NCK2 Produits)

Synonymes: GRB4 Protein, NCKbeta Protein, NCK2 Protein, 4833426I10Rik Protein, Grb4 Protein, Nck-2 Protein, Nck2 Protein, zgc:55283 Protein, fd20h08 Protein, im:7147817 Protein, si:ch211-147g19.3 Protein, wu:fd20h08 Protein, zgc:92024 Protein, NCK adaptor protein 2 Protein, cytoplasmic protein NCK2-like Protein, non-catalytic region of tyrosine kinase adaptor protein 2 Protein, NCK adaptor protein 2a Protein, NCK adaptor protein 2b Protein, NCK2 Protein, Nck2 Protein, LOC100227348 Protein, nck2a Protein, nck2b Protein

Sujet: NCK2 is a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptiona splice variants, encoding different isoforms, have been characterized. Recombinant human NCK2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 45.3 kDa (403aa) confirmed by MALDI-TOF

NCBI Accession: NP_003572

UniProt: O43639

Pathways: EGFR Signaling Pathway, Regulation of Actin Filament Polymerization