PRRT2 Protein (AA 1-268) (His tag)

N° du produit ABIN5853508

Détail du produit

Antigène: PRRT2 (Proline-Rich Transmembrane Protein 2 (PRRT2))

Type de proteíne: Recombinant

Attributs du protein: AA 1-268

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette PRRT2 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSMAASSSE ISEMKGVEES PKVPGEGPGH SEAETGPPQV LAGVPDQPEA PQPGPNTTAA PVDSGPKAGL APETTETPAG ASETAQATDL SLSPGGESKA NCSPEDPCQE TVSKPEVSKE ATADQGSRLE SAAPPEPAPE PAPQPDPRPD SQPTPKPALQ PELPTQEDPT PEILSESVGE KQENGAVVPL QAGDGEEGPA PEPHSPPSKK SPPANGAPPR VLQQLVEEDR MRRAHSGHPG SPRGSLSRHP SSQLAGPGVE GGEGTQKPRD Y

Pureté: > 85 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.15M NaCl, 10 % glycerol, 1  mM DTT.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: PRRT2 (Proline-Rich Transmembrane Protein 2 (PRRT2))

Autre désignation: PRRT2 (PRRT2 Produits)

Synonymes: BFIC2 Protein, BFIS2 Protein, DSPB3 Protein, DYT10 Protein, EKD1 Protein, ICCA Protein, IFITMD1 Protein, PKC Protein, 1500031I19Rik Protein, AI195361 Protein, proline rich transmembrane protein 2 Protein, proline-rich transmembrane protein 2 Protein, PRRT2 Protein, Prrt2 Protein

Sujet: PRRT2 is a transmembrane protein containing a proline-rich domain in its N-terminal half. Studies in mice suggest that it is predominantly expressed in brain and spinal cord in embryonic and postnatal stages. Mutations in this gene are associated with paroxysmal kinesigenic dyskinesia. Almost one third of sporadic PKC patients also carry PRRT2 mutations. Recombinant human PRRT2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 29.7 kDa (291aa) confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)

NCBI Accession: NP_001243372

UniProt: Q7Z6L0