STEAP4 Protein (AA 1-152) (His tag)

N° du produit ABIN5853589

Détail du produit

Antigène: STEAP4 (STEAP Family Member 4 (STEAP4))

Type de proteíne: Recombinant

Attributs du protein: AA 1-152

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette STEAP4 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMEKT CIDALPLTMN SSEKQETVCI FGTGDFGRSL GLKMLQCGYS VVFGSRNPQK TTLLPSGAEV LSYSEAAKKS GIIIIAIHRE HYDFLTELTE VLNGKILVDI SNNLKINQYP ESNAEYLAHL VPGAHVVKAF NTISAWALQS GALDASRQ

Pureté: > 90 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Denatured

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.4M uREA, 10 % glycerol

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: STEAP4 (STEAP Family Member 4 (STEAP4))

Autre désignation: STEAP4 (STEAP4 Produits)

Synonymes: STAMP2 Protein, TIARP Protein, TNFAIP9 Protein, MGC68826 Protein, STEAP4 Protein, MGC108044 Protein, steap4 Protein, 1110021O17Rik Protein, AI481214 Protein, Tiarp Protein, Tnfaip9 Protein, si:dkey-53p21.1 Protein, zgc:112143 Protein, STEAP4 metalloreductase Protein, STEAP4 metalloreductase L homeolog Protein, metalloreductase STEAP4 Protein, STEAP family member 4 Protein, STEAP4 Protein, steap4.L Protein, Steap4 Protein, steap4 Protein, LOC100136336 Protein, LOC100353852 Protein

Sujet: STEAP4 belongs to the STEAP (six transmembrane epithelial antigen of prostate) family, and resides in the golgi apparatus. It functions as a metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+),using NAD(+) as acceptor. Studies in mice and human suggest that this gene maybe involved in adipocyte development and metabolism, and may contribute to the normal biology of the prostate cell, as well as prostate cancer progression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Recombinant human STEAP4 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Poids moléculaire: 20.6kDa (188aa)

NCBI Accession: NP_078912

UniProt: Q687X5

Pathways: Transition Metal Ion Homeostasis