SVIP Protein (AA 1-77) (His tag)
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- Antigène Voir toutes SVIP Protéines
- SVIP (Small VCP/p97-Interacting Protein (SVIP))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-77
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette SVIP protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Séquence
- MGSSHHHHHH SSGLVPRGSH MGSMGLCFPC PGESAPPTPD LEEKRAKLAE AAERRQKEAA SRGILDVQSV QEKRKKKEKI EKQIATSGPP PEGGLRWTVS
- Pureté
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product SVIP Protéine
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.15M NaCl, 20 % glycerol, 2 mM DTT
- Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Antigène
- SVIP (Small VCP/p97-Interacting Protein (SVIP))
- Autre désignation
- SVIP (SVIP Produits)
- Synonymes
- 1700006C13Rik Protein, 6620401M08Rik Protein, RGD1565432 Protein, small VCP interacting protein Protein, small VCP/p97-interacting protein Protein, SVIP Protein, Svip Protein
- Sujet
- Small VCP/p97-interacting protein, also known as SVIP, is involved in a variety of cellular processes, including membrane fusion and ubiquitin-dependent protein degradation. SVIP functions as an inhibitor of the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway. Overexpression of SVIP, on the other hand, increased the levels of p62 protein and enhanced starvation-activated autophagy as well as promoted sequestration of polyubiquitinated proteins and p62 in autophagosomes. Recombinant human SVIP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Poids moléculaire
- 10.8kDa (100aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_683691
- UniProt
- Q8NHG7
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