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Neurogranin Protein (NRGN) (AA 1-78) (His tag)

NRGN Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
N° du produit ABIN5853774
  • Antigène Voir toutes Neurogranin (NRGN) Protéines
    Neurogranin (NRGN)
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 1-78
    Origine
    • 7
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 3
    • 3
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette Neurogranin protéine est marqué à la His tag.
    Application
    SDS-PAGE (SDS)
    Séquence
    MGSSHHHHHH SSGLVPRGSH MGSMDCCTEN ACSKPDDDIL DIPLDDPGAN AAAAKIQASF RGHMARKKIK SGERGRKGPG PGGPGGAGVA RGGAGGGPSG D
    Pureté
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product NRGN Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Liquid. 20  mM Tris-HCl buffer (  pH 7.0) containing 30 % glycerol 0.1  mM PMSF,1  mM EDTA
    Stock
    4 °C,-20 °C,-80 °C
    Stockage commentaire
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Antigène
    Neurogranin (NRGN)
    Autre désignation
    NRGN (NRGN Produits)
    Synonymes
    RC3 Protein, hng Protein, 0710001B06Rik Protein, AI838505 Protein, NG Protein, NG/RC3 Protein, Pss1 Protein, R75334 Protein, zgc:158686 Protein, neurogranin Protein, neurogranin (protein kinase C substrate, RC3) b Protein, NRGN Protein, Nrgn Protein, nrgnb Protein
    Sujet
    NRGN, also known as Neurogranin, is a calmodulin-binding protein expressed exclusively in the brain, particularly in dendritic spines, and participating in the protein kinase C signaling pathway. This protein is the main postsynaptic protein regulating the availability of calmodulin, binding to it in the absence of calcium. Phosphorylation by protein kinase C lowers its binding ability. Recombinant human NRGN protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography
    Poids moléculaire
    10.0 kDa(101aa) confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)
    NCBI Accession
    NP_001119653
    UniProt
    Q92686
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