LOX Protein (AA 169-417) (His tag)

N° du produit ABIN5853903

Détail du produit

Antigène: LOX (Lysyl Oxidase (LOX))

Type de proteíne: Recombinant

Attributs du protein: AA 169-417

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette LOX protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSDDPYNPY KYSDDNPYYN YYDTYERPRP GGRYRPGYGT GYFQYGLPDL VADPYYIQAS TYVQKMSMYN LRCAAEENCL ASTAYRADVR DYDHRVLLRF PQRVKNQGTS DFLPSRPRYS WEWHSCHQHY HSMDEFSHYD LLDANTQRRV AEGHKASFCL EDTSCDYGYH RRFACTAHTQ GLSPGCYDTY GADIDCQWID ITDVKPGNYI LKVSVNPSYL VPESDYTNNV VRCDIRYTGH HAYASGCTIS PY

Pureté: > 85 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Denatured

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 10 % glycerol

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: LOX (Lysyl Oxidase (LOX))

Autre désignation: LOX (LOX Produits)

Synonymes: LOX Protein, Xlox Protein, MGC146507 Protein, lox Protein, zgc:77447 Protein, AI893619 Protein, TSC-160 Protein, H-rev142 Protein, Rrg1 Protein, lysyl oxidase Protein, lysyl oxidase a Protein, lysyl oxidase L homeolog Protein, LOX Protein, lox Protein, loxa Protein, lox.L Protein, Lox Protein

Sujet: LOX is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene. Recombinant human LOX protein, fused to His-tag at N-terminus, was expressed in E.coli.

Poids moléculaire: 31.4 kDa (272aa)

NCBI Accession: NP_002308

UniProt: P28300

Pathways: SARS-CoV-2 Protein Interactome