NFU1 Protein (AA 10-254) (His tag)

N° du produit ABIN5853977

Détail du produit

Antigène: NFU1 (NFU1 Iron-Sulfur Cluster Scaffold (NFU1))

Type de proteíne: Recombinant

Attributs du protein: AA 10-254

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette NFU1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSGAAAVAA GLRRRFCHML KNPYTIKKQP LHQFVQRPLF PLPAAFYHPV RYMFIQTQDT PNPNSLKFIP GKPVLETRTM DFPTPAAAFR SPLARQLFRI EGVKSVFFGP DFITVTKENE ELDWNLLKPD IYATIMDFFA SGLPLVTEET PSGEAGSEED DEVVAMIKEL LDTRIRPTVQ EDGGDVIYKG FEDGIVQLKL QGSCTSCPSS IITLKNGIQN MLQFYIPEVE GVEQVMDDES DEKEANSP

Pureté: > 90 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In Phosphate buffer saline (  pH 7.4) containing 20 % glycerol 1  mM DTT

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: NFU1 (NFU1 Iron-Sulfur Cluster Scaffold (NFU1))

Autre désignation: NFu1 (NFU1 Produits)

Synonymes: HIRIP Protein, HIRIP5 Protein, MMDS1 Protein, NIFUC Protein, Nfu Protein, NifU Protein, 0610006G17Rik Protein, CGI-33 Protein, Hirip5 Protein, NFU1 iron-sulfur cluster scaffold Protein, NFU1 Protein, Nfu1 Protein

Sujet: NFu1 is a protein that is localized to mitochondria and plays a critical role in iron-sulfur cluster biogenesis. This protein assembles and transfers 4Fe-4S clusters to target apoproteins including succinate dehydrogenase and lipoic acid synthase. Mutations in this gene are a cause of bmultiple mitochondrial dysfunctions syndrome-1, and pseudogenes of this gene are located on the short arms of chromosomes 1 and 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Recombinant human NFu1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 29.9 kDa (268aa) confirmed by MALDI-TOF

NCBI Accession: NP_001002755

UniProt: Q9UMS0