MGC84401 Protein, fgfbp Protein, hbp17 Protein, FGF-BP Protein, FGF-BP1 Protein, FGFBP Protein, FGFBP-1 Protein, HBP17 Protein, fibroblast growth factor binding protein 1 S homeolog Protein, fibroblast growth factor binding protein 1 Protein, fibroblast growth factor-binding protein 1 Protein, fgfbp1.S Protein, FGFBP1 Protein, fgfbp1 Protein, Fgfbp1 Protein, LOC100726816 Protein, LOC101106941 Protein
Sujet
FGFBP1 is a secreted fibroblast growth factor carrier protein. This protein plays a critical role in cell proliferation, differentiation and migration by binding to fibroblast growth factors and potentiating their biological effects on target cells. It may also play a role in tumor growth as an angiogenic switch molecule, and expression of this gene has been associated with several types of cancer including pancreatic and colorectal adenocarcinoma. Recombinant human FGFBP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.