CHRNA3 Protein (AA 32-240) (His tag)

N° du produit ABIN5854260

Détail du produit

Antigène: CHRNA3 (Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) (CHRNA3))

Type de proteíne: Recombinant

Attributs du protein: AA 32-240

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette CHRNA3 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSSEAEHRL FERLFEDYNE IIRPVANVSD PVIIHFEVSM SQLVKVDEVN QIMETNLWLK QIWNDYKLKW NPSDYGGAEF MRVPAQKIWK PDIVLYNNAV GDFQVDDKTK ALLKYTGEVT WIPPAIFKSS CKIDVTYFPF DYQNCTMKFG SWSYDKAKID LVLIGSSMNL KDYWESGEWA IIKAPGYKHD IKYNCCEEIY PDITYSLYIR RL

Pureté: > 80 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Denatured

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer(  pH 8.0) containing 10 % glycerol

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: CHRNA3 (Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) (CHRNA3))

Autre désignation: CHRNA3 (CHRNA3 Produits)

Synonymes: LNCR2 Protein, NACHRA3 Protein, PAOD2 Protein, (a)3 Protein, A730007P14Rik Protein, Acra-3 Protein, Acra3 Protein, cholinergic receptor nicotinic alpha 3 subunit Protein, cholinergic receptor, nicotinic, alpha polypeptide 3 Protein, CHRNA3 Protein, Chrna3 Protein

Sujet: CHRNA3 also known as neuronal acetylcholine receptor subunit alpha-3 isoform 1 is a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. CHRNA3 is a ligand-gated ion channel that likely plays a role in neurotransmission. CHRNA3 have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. Recombinant human CHRNA3 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Poids moléculaire: 27kDa (232aa)

NCBI Accession: NP_000734

UniProt: P32297

Pathways: Synaptic Membrane