LRPAP1 Protein (AA 29-360) (His tag)

N° du produit ABIN5854296

Détail du produit

Antigène: LRPAP1 (Low Density Lipoprotein Receptor-Related Protein Associated Protein 1 (LRPAP1))

Type de proteíne: Recombinant

Attributs du protein: AA 29-360

Origine: Souris

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette LRPAP1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSQPIAGHG GKYSREKNEP EMAAKRESGE EFRMEKLNQL WEKAKRLHLS PVRLAELHSD LKIQERDELN WKKLKVEGLD KDGEKEAKLI HNLNVILARY GLDGRKDAQM VHSNALNEDT QDELGDPRLE KLWHKAKTSG KFSSEELDKL WREFLHYKEK IQEYNVLLDT LSRAEEGYEN LLSPSDMAHI KSDTLISKHS ELKDRLRSIN QGLDRLRKVS HQGYGSTTEF EEPRVIDLWD LAQSANFTEK ELESFREELK HFEAKIEKHN HYQKQLEISH QKLKHVESIG DPEHISRNKE KYVLLEEKTK ELGYKVKKHL QDLSSRVSRA RHNEL

Pureté: > 90 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid, In Phosphate buffered saline (  pH 7.4) containing 10 % glycerol

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: LRPAP1 (Low Density Lipoprotein Receptor-Related Protein Associated Protein 1 (LRPAP1))

Autre désignation: Lrpap1 (LRPAP1 Produits)

Synonymes: wu:fi20f07 Protein, wu:fi22c06 Protein, LRPAP1 Protein, DKFZp459I2430 Protein, A2MRAP Protein, A2RAP Protein, HBP44 Protein, MRAP Protein, RAP Protein, AA617339 Protein, AI790446 Protein, AU042172 Protein, C77774 Protein, alpha-2-macroglobulin receptor-associated protein-like Protein, low density lipoprotein receptor-related protein associated protein 1 Protein, LDL receptor related protein associated protein 1 Protein, LDL receptor related protein associated protein 1 L homeolog Protein, LOC100231803 Protein, lrpap1 Protein, LRPAP1 Protein, Lrpap1 Protein, lrpap1.L Protein

Sujet: Lrpap1 also known as Alpha-2-macroglobulin receptor-associated protein. The alpha-2-macroglobulin receptor-associated protein (RAP) is a glycoprotein that binds to the alpha-2-macroglobulin receptor, as well as to other members of the low density lipoprotein receptor family. Lrpap1 acts to inhibit the binding of all know ligands for these receptors, and may prevent receptor aggregation and degradation in the endoplasmic reticulum, thereby acting as a molecular chaperone. Lrpap1 may be under the regulatory control of calmodulin, since it is able to bind calmodulin and be phosphorylated by calmodulin-dependent kinase II. Recombinant mouse Lspap1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 41.4kDa (355aa) confirmed by MALDI-TOF

NCBI Accession: NP_038615

UniProt: P55302