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Chorionic Gonadotropin, beta Polypeptide 3 (CGB3) (AA 21-165) protein (His tag)

CGB3 Origine: Humain Hôte: Baculovirus infected Insect Cells Recombinant > 90 % by SDS - PAGE SDS
N° du produit ABIN5854819
  • Antigène Tous les produits Chorionic Gonadotropin, beta Polypeptide 3 (CGB3)
    Chorionic Gonadotropin, beta Polypeptide 3 (CGB3)
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 21-165
    Origine
    Humain
    Source
    • 1
    Baculovirus infected Insect Cells
    Purification/Conjugué
    His tag
    Application
    SDS-PAGE (SDS)
    Séquence
    ADPSKEPLRP RCRPINATLA VEKEGCPVCI TVNTTICAGY CPTMTRVLQG VLPALPQVVC NYRDVRFESI RLPGCPRGVN PVVSYAVALS CQCALCRRST TDCGGPKDHP LTCDDPRFQD SSSSKAPPPS LPSPSRLPGP SDTPILPQHH HHHH
    Pureté
    > 90 % by SDS - PAGE
    niveau d'endotoxine
    < 1.0 EU per 1 microgram of protein (determined by LAL method)
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.
    Stock
    4 °C,-20 °C,-80 °C
    Stockage commentaire
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Antigène
    Chorionic Gonadotropin, beta Polypeptide 3 (CGB3)
    Autre désignation
    CGB3 (CGB3 Produits)
    Synonymes
    CGB3 Protein, CGB5 Protein, CGB7 Protein, CGB8 Protein, hCGB Protein, chorionic gonadotropin beta subunit 3 Protein, CGB3 Protein
    Sujet
    CGB3, also known as choriogonadotropin subunit beta, is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). It stimulates the expression of GCM1 target genes, including the fusogenic protein syncytin-1, to promote placental cell fusion. It synthesized in large quantities by the developing placenta, reaching peak concentrations in maternal blood during the late first trimester and early midtrimester of pregnancy. It is expressed exclusively by trophoblasts. It is an important biomarker in pregnancy and oncology, where it is routinely detected and quantified by specific immunoassays. Recombinant human CGB3, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
    Poids moléculaire
    16.6kDa (154aa) 18-28kDa (SDS-PAGE under reducing conditions)
    NCBI Accession
    NP_000728
    UniProt
    P0DN86
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