CD48 Protein (CD48) (AA 27-220) (His tag)

N° du produit ABIN7281272

Détail du produit

Antigène: CD48

Type de proteíne: Recombinant

Attributs du protein: AA 27-220

Origine: Humain

Source: Baculovirus infected Insect Cells

Purification/Conjugué: Cette CD48 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: ADPQGHLVHM TVVSGSNVTL NISESLPENY KQLTWFYTFD QKIVEWDSRK SKYFESKFKG RVRLDPQSGA LYISKVQKED NSTYIMRVLK KTGNEQEWKI KLQVLDPVPK PVIKIEKIED MDDNCYLKLS CVIPGESVNY TWYGDKRPFP KELQNSVLET TLMPHNYSRC YTCQVSNSVS SKNGTVCLSP PCTLARSHHH HHH

Pureté: > 90 % by SDS - PAGE

niveau d'endotoxine: < 1.0 EU per 1ug of protein (determined by LAL method)

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: CD48

Autre désignation: CD48 (CD48 Produits)

Synonymes: AI449234 Protein, AW610730 Protein, BCM1 Protein, BLAST Protein, BLAST-1 Protein, BLAST1 Protein, Bcm-1 Protein, MEM-102 Protein, SLAMF2 Protein, Sgp-60 Protein, hCD48 Protein, mCD48 Protein, CD48 antigen Protein, Cd48 molecule Protein, CD48 molecule Protein, Cd48 Protein, CD48 Protein

Sujet: CD48, also known as CD48 antigen isoform 1, is a GPI-linked protein in the CD2 family of immunoglobulin superfamily molecules. This protein is competent to transduce signals and can also trigger signaling through CD2 or 2B4. CD48-CD2 interactions promote T cell activation and class switching to IgG2a in B cells. High affinity CD48-2B4 interactions can either promote or inhibit NK cell and cytotoxic T cell (CTL) activation. It expressed on NK cells is coactivating, whereas CD48 expressed on other cell types inhibits NK cell activation. Recombinant human CD48, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Poids moléculaire: 23.4kDa (203aa) 28-40kDa (SDS-PAGE under reducing conditions.)

NCBI Accession: NP_001769

UniProt: P09326