Recoverin Protein (RCVRN) (AA 33-293) (His tag)

N° du produit ABIN7281368

Détail du produit

Antigène: Recoverin (RCVRN)

Type de proteíne: Recombinant

Attributs du protein: AA 33-293

Origine: Souris

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette Recoverin protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSMGNSKSG ALSKEILEEL QLNTKFTEEE LSAWYQSFLK ECPSGRITRQ EFESIYSKFF PDSDPKAYAQ HVFRSFDANS DGTLDFKEYV IALHMTTAGK PTQKLEWAFS LYDVDGNGTI SKNEVLEIVM AIFKMIKPED VKLLPDDENT PEKRAEKIWA FFGKKEDDKL TEEEFIEGTL ANKEILRLIQ FEPQKVKERI KEKKQ

Pureté: > 90 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol, 1  mM DTT

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: Recoverin (RCVRN)

Autre désignation: Recoverin (RCVRN Produits)

Synonymes: RCV1 Protein, CAR Protein, S-modulin Protein, Rcv1 Protein, rcv1 Protein, rcvrn Protein, recoverin Protein, reco Protein, recoverin Protein, recoverin, gene 2 S homeolog Protein, recoverin, gene 2 L homeolog Protein, Recoverin Protein, RCVRN Protein, Rcvrn Protein, rcvrn.2.S Protein, rcvrn.2.L Protein, reco Protein

Sujet: Recoverin also known as Rcvrn, is a heterogeneously acylated calcium-binding and intracellular signal transduction protein in the photoreceptor cells of retina. Recoverin contains four EF-hands, of which two bind Ca. Ca-induced extrusion of the acyl group from a hydrophobic cleft in the protein drives the translocation of recoverin from solution to the disc membrane. Recently, recoverin is a detectable serologic protein that is expressed in patients with cancer-associated retinopathy, a paraneoplastic syndrome. Recombinant Mouse recoverin, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Poids moléculaire: 25.8kDa (225aa)

NCBI Accession: NP_033064

UniProt: P34057

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction