HARS1/Jo-1 Protéine

N° du produit ABIN622883

Détail du produit

Antigène: HARS1/Jo-1 (HARS1) (Histidyl-tRNA Synthetase (HARS1))

Type de proteíne: Recombinant

Origine: Humain

Hôte: Veuillez nous consulter SVP

Attributs du produit: Recombinant Human Histidyl-tRNA Synthetase

Pureté: > 90.0 % as determined by both (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Protein quantitation was carried out by using 0.25 - 2.0 mg/ml Bradford assay vs. BSA. Western Blotting Strongly reactive with human anti Histidyl-tRNA Synthetase antisera.

Buffer: The protein solution contains 150mM NaCl and 10mM sodium phosphate containing 0.1% NaN3 (pH 7.2).

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détail du antigène

Antigène: HARS1/Jo-1 (HARS1) (Histidyl-tRNA Synthetase (HARS1))

Autre désignation: Histidyl-tRNA Synthetase (HARS1 Produits)

Synonymes: HRS Protein, USH3B Protein, MMHRS Protein, Dnd1 Protein, HARSL Protein, histidyl-tRNA synthetase Protein, HARS Protein, Hars Protein

Sujet: Histidyl-tRNA Synthetase Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain having a molecular mass of 55 kDa. The Histidyl-tRNA Synthetase is purified by proprietary chromatographic techniques. Introduction: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis. Synonyms: Histidyl-tRNA synthetase, EC 6.1.1.21, Histidine-tRNA ligase, HisRS, HRS, FLJ20491, JO-1.