PFDN1 Protein (AA 14-122) (His tag)

N° du produit ABIN6386632

Détail du produit

Antigène: PFDN1 (Prefoldin Subunit 1 (PFDN1))

Type de proteíne: Recombinant

Attributs du protein: AA 14-122

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette PFDN1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: PFDN1, 14-122aa, Human, His tag, E.coli

Pureté: > 90 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 20% Glycerol

Stock: 4 °C

Détail du antigène

Antigène: PFDN1 (Prefoldin Subunit 1 (PFDN1))

Autre désignation: PFDN1 (PFDN1 Produits)

Synonymes: PFDN1 Protein, 2700086I23Rik Protein, AA408327 Protein, AU044714 Protein, PDF Protein, PFD1 Protein, zgc:110742 Protein, prefoldin subunit 1 Protein, prefoldin 1 Protein, prefoldin subunit 1 S homeolog Protein, PFDN1 Protein, AFUA_4G12360 Protein, pfdn1 Protein, Pfdn1 Protein, pfdn1.S Protein

Sujet: PFDN1 is one of sixsubunits of prefoldin, a heterohexameric chaperone protein which assists in the correct folding of other proteins. This protein delivers nonnative target proteins, principally actins and tubulins, to the eukaryotic cytosolic chaperonin for facilitated folding. Defects in PFDN1 displayed phenotypes characteristic of defects in cytoskeletal function, including manifestations of ciliary dyskinesia, neuronal loss, and defects in B and T cell development and function. Recombinant human PFDN1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Prefoldin subunit 1, PDF, PFD1. NCBI no.: NP_002613

Poids moléculaire: 15.0kDa (130aa), confirmed by MALDI-TOF

Pathways: Unfolded Protein Response