TNIP1 Protein (AA 94-530) (His tag)

N° du produit ABIN667262

Détail du produit

Antigène: TNIP1 (TNFAIP3 Interacting Protein 1 (TNIP1))

Type de proteíne: Recombinant

Attributs du protein: AA 94-530

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette TNIP1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: TNIP1, 94-530aa, Human, His tag, E.coli

Pureté: > 75 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH7.5) containing 20% glycerol, 5mM DTT, 200mM NaCl

Stock: 4 °C

Détail du antigène

Antigène: TNIP1 (TNFAIP3 Interacting Protein 1 (TNIP1))

Autre désignation: TNIP1 (TNIP1 Produits)

Synonymes: ABIN-1 Protein, NAF1 Protein, VAN Protein, nip40-1 Protein, ABIN Protein, ABIN1 Protein, AU018810 Protein, Naf1 Protein, Nef Protein, im:7141452 Protein, naf1 Protein, zgc:158159 Protein, tnip1 Protein, MGC147597 Protein, TNFAIP3 interacting protein 1 Protein, TNFAIP3 interacting protein 1 S homeolog Protein, TNFAIP3-interacting protein 1 Protein, TNIP1 Protein, Tnip1 Protein, tnip1 Protein, tnip1.S Protein, LOC100078195 Protein

Sujet: TNIP1 (TNFAIP3-interacting protein 1) has been shown to interacts with zinc finger protein A20/TNFAIP3 and inhibits TNF-induced NF-kappa-B-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal. In addition, interacts with HIV-1 matrix protein and is packaged into virions and overexpression can inhibit viral replication. It may regulate matrix nuclear localization, both nuclear import of PIC (Preintegration complex) and export of GAG polyprotein and viral genomic RNA during virion production. Recombinant human TNIP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: TNFAIP3 interacting protein 1, ABIN-1, NAF1, VAN, Nip40-1. NCBI no.: NP_006049

Poids moléculaire: 51.8kDa (458aa) confirmed by MALDI-TOF

Pathways: Activation of Innate immune Response