HUS1 Protein (AA 1-280) (His tag)
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- Antigène Voir toutes HUS1 Protéines
- HUS1 (HUS1 Checkpoint Homolog (S. Pombe) (HUS1))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-280
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette HUS1 protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Attributs du produit
- HUS1, 1-280aa, Human, His tag, E.coli
- Pureté
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product HUS1 Protéine
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 100 mM NaCl, 40% Glycerol
- Stock
- 4 °C
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- Antigène
- HUS1 (HUS1 Checkpoint Homolog (S. Pombe) (HUS1))
- Autre désignation
- HUS1 (HUS1 Produits)
- Synonymes
- hHUS1 Protein, mHus1 Protein, XHus1 Protein, hus1 Protein, HUS1 checkpoint clamp component Protein, checkpoint clamp complex protein Hus1 Protein, HUS1 checkpoint clamp component L homeolog Protein, HUS1 Protein, Hus1 Protein, hus1 Protein, hus1.L Protein
- Sujet
- HUS1 is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex. This protein associates with Rad9 and Rad1 to form the 9-1-1(RAD9-RAD1-HUS1) complex, which localizes to DNA lesions and promotes DNA damage signaling and repair or apoptosis, cell cycle arrest. The trimeric complex is structurally similar to the proliferating cell nuclear antigen (PCNA) sliding clamp and interacts with Rad17 as a clamp-clamp loader pair during the DNA damage response. Recombinant human HUS1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: checkpoint protein HUS1,. NCBI no.: NP_004498
- Poids moléculaire
- 33.8 kDa (300aa), confirmed by MALDI-TOF
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