CDC25A Protein (AA 1-524) (His tag)

N° du produit ABIN6386706

Détail du produit

Antigène: CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))

Type de proteíne: Recombinant

Attributs du protein: AA 1-524

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette CDC25A protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: CDC25A, 1-524aa, Human, His tag, E.coli

Pureté: > 80 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 5mM DTT, 20% glycerol, 0.2M NaCl, 1mM EDTA

Stock: 4 °C

Détail du antigène

Antigène: CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))

Autre désignation: CDC25A (CDC25A Produits)

Synonymes: cdc25a2 Protein, cdc25A Protein, sb:cb317 Protein, CDC25A2 Protein, D9Ertd393e Protein, cell division cycle 25A Protein, cell division cycle 25B Protein, cell division cycle 25A S homeolog Protein, CDC25A Protein, cdc25a Protein, cdc25b Protein, Cdc25a Protein, cdc25a.S Protein

Sujet: M-phase inducer phosphatase 1, also known as CDC25A, is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Recombinant human CDC25A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: M-phase inducer phosphatase 1, Dual specificity phosphatase Cdc25A, Cdc 25a, Cell division cycle 25 homolog A (S. pombe), Cell division cycle 25A, Cell division cycle 25A isoform a, Cell division cycle 25A isoform b, D9Ertd393e, EC 3.1.3.48, M phase inducer phosphatase 1, MGC115549. NCBI no.: NP_001780

Poids moléculaire: 63.2 kDa (560aa)

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases, M Phase