RYBP Protein (His tag)

N° du produit ABIN1098318

Détail du produit

Antigène: RYBP (RING1 and YY1 Binding Protein (RYBP))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette RYBP protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Purification: purified by chromatography

Pureté: > 85 % by SDS - PAGE

Information d'application

Commentaires:

Synonyms: RING1 and YY1 binding protein, AAP1, DEDAF, YEAF1

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer, pH 8.0, 20% glycerol, 1 MM DTT, 100 mM NaCl

Stock: 4 °C

Stockage commentaire: Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: RYBP (RING1 and YY1 Binding Protein (RYBP))

Autre désignation: RYBP (RYBP Produits)

Synonymes: AAP1 Protein, DEDAF Protein, YEAF1 Protein, 2410018J24Rik Protein, rybp Protein, aap1 Protein, dedaf Protein, yeaf1 Protein, cb337 Protein, wu:fi34f03 Protein, Dedaf Protein, zgc:153842 Protein, RING1 and YY1 binding protein Protein, RING1 and YY1 binding protein L homeolog Protein, RING1 and YY1 binding protein a Protein, RING1 and YY1 binding protein b Protein, RYBP Protein, Rybp Protein, rybp Protein, rybp.L Protein, rybpa Protein, rybpb Protein

Sujet: RYBP (RING1- and YY1-binding protein) is a member of the polycomb group (PcG). This protein interacts with MDM2 and decreases MDM2-mediated p53 ubiquitination, leading to stabilization of p53 and an increase in p53 activity. RYBP induces cell-cycle arrest and is involved in the p53 response to DNA damage. RYBP has been shown to interact with RING1, YY1, Caspase 10, E2F3, E2F2, Mdm2, Abl gene and CBX2. Recombinant human RYBP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 27.4kDa (252aa) confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)

NCBI Accession: NP_036366