NHEJ1 Protein (His tag)
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- Antigène Voir toutes NHEJ1 Protéines
- NHEJ1 (Nonhomologous End-Joining Factor 1 (NHEJ1))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette NHEJ1 protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Pureté
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product NHEJ1 Protéine
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Nonhomologous End-Joining Factor 1 (NHEJ1) (AA 1-224) protein (His tag)
NHEJ1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Nonhomologous End-Joining Factor 1 (NHEJ1) (AA 1-299) protein (GST tag)NHEJ1 Origine: Humain Hôte: Wheat germ Recombinant ELISA, WB, AP, AA
Nonhomologous End-Joining Factor 1 (NHEJ1) (AA 1-299) protein (Strep Tag)Crystallography grade NHEJ1 Origine: Humain Hôte: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Nonhomologous End-Joining Factor 1 (NHEJ1) (AA 1-295) protein (Strep Tag)Crystallography grade NHEJ1 Origine: Souris Hôte: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Nonhomologous End-Joining Factor 1 (NHEJ1) protein (Myc-DYKDDDDK Tag)NHEJ1 Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Commentaires
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Synonyms: Non-homologous end-joining factor 1, XLF
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 20% glycerol,1 MM DTT
- Stock
- 4 °C
- Stockage commentaire
- Avoid repeated freezing and thawing cycles.
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- Antigène
- NHEJ1 (Nonhomologous End-Joining Factor 1 (NHEJ1))
- Autre désignation
- NHEJ1 (NHEJ1 Produits)
- Synonymes
- NHEJ1 Protein, zgc:85657 Protein, XLF Protein, 1700029B21Rik Protein, cernunnos Protein, non-homologous end joining factor 1 Protein, non-homologous end joining factor 1 S homeolog Protein, solute carrier family 23 member 3 Protein, nonhomologous end-joining factor 1 Protein, NHEJ1 Protein, nhej1.S Protein, nhej1 Protein, SLC23A3 Protein, Nhej1 Protein
- Sujet
- Non-homologous end-joining factor 1, also known as NHEJ1, belongs to the XLF family. NHEJ1 was originally discovered as the protein mutated in five patients with growth retardation, microcephaly, and immunodeficiency. The protein is required for the non-homologous end joining (NHEJ) pathway of DNA repair. Patients with NHEJ1 mutations also have immunodeficiency due to a defect in V(D)J recombination, which utilizes NHEJ to promote immune system diversity. XLF interacts with DNA ligase IV and XRCC4 and is thought to be involved in the ligation step of NHEJ. Recombinant human NHEJ1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Poids moléculaire
- 27.8 kDa (247aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_079058
- Pathways
- Réparation de l'ADN
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