TARDBP Protein (His tag)
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- Antigène Voir toutes TARDBP Protéines
- TARDBP (TAR DNA Binding Protein (TARDBP))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette TARDBP protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Pureté
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product TARDBP Protéine
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- Commentaires
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Synonyms: TAR DNA binding protein, ALS10, TDP43
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.1 M NaCl
- Stock
- 4 °C
- Stockage commentaire
- Avoid repeated freezing and thawing cycles.
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- Antigène
- TARDBP (TAR DNA Binding Protein (TARDBP))
- Autre désignation
- TARDBP (TARDBP Produits)
- Synonymes
- TARDBP Protein, TDP43 Protein, DKFZp459I2127 Protein, tardbp Protein, ALS10 Protein, TDP-43 Protein, 1190002A23Rik Protein, C85084 Protein, Tdp43 Protein, wu:fb77f02 Protein, wu:fc52g10 Protein, TAR DNA binding protein Protein, Tardbp protein Protein, TAR DNA binding protein L homeolog Protein, TAR DNA-binding protein 43-like Protein, TARDBP Protein, tardbp Protein, tardbp.L Protein, Tardbp Protein, LOC100621383 Protein
- Sujet
- TARDBP was originally identified as a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. It has also been identified in individuals diagnosed with chronic traumatic encephalopathy, a condition that often mimics ALS and that has been associated with athletes who have experienced multiple concussions and other types of head injury. It has been shown to bind both DNA and RNA and have multiple functions in transcriptional repression, pre-mRNA splicing and translational regulation. Recombinant human TARDBP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques
- Poids moléculaire
- 33.6 kDa(296aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_031401
- Pathways
- Positive Regulation of Peptide Hormone Secretion
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