FBLIM1 Protein (AA 1-373) (His tag)

N° du produit ABIN6387197

Détail du produit

Antigène: FBLIM1 (Filamin Binding LIM Protein 1 (FBLIM1))

Type de proteíne: Recombinant

Attributs du protein: AA 1-373

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette FBLIM1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSMASKPEK RVASSVFITL APPRRDVAVA EEVRQAVCEA RRGRPWEAPA PMKTPEAGLA GRPSPWTTPG RAAATVPAAP MQLFNGGCPP PPPVLDGEDV LPDLDLLPPP PPPPPVLLPS EEEAPAPMGA SLIADLEQLH LSPPPPPPQA PAEGPSVQPG PLRPMEEELP PPPAEPVEKG ASTDICAFCH KTVSPRELAV EAMKRQYHAQ CFTCRTCRRQ LAGQSFYQKD GRPLCEPCYQ DTLERCGKCG EVVRDHIIRA LGQAFHPSCF TCVTCARCIG DESFALGSQN EVYCLDDFYR KFAPVCSICE NPIIPRDGKD AFKIECMGRN FHENCYRCED CRILLSVEPT DQGCYPLNNH LFCKPCHVKR SAAGCC

Pureté: > 85 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.15M NaCl, 10 % glycerol, 1  mM DTT

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: FBLIM1 (Filamin Binding LIM Protein 1 (FBLIM1))

Autre désignation: FBLIM1 (FBLIM1 Produits)

Synonymes: FBLIM1 Protein, CAL Protein, FBLP-1 Protein, FBLP1 Protein, 2410043F08Rik Protein, Cal Protein, Fblp1 Protein, Gt10 Protein, migfilin Protein, migfilin(s) Protein, filamin binding LIM protein 1 Protein, filamin binding LIM protein 1 S homeolog Protein, FBLIM1 Protein, fblim1.S Protein, Fblim1 Protein

Sujet: Filamin binding LIM protein 1, also known as FBLIM1, serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. This protein is implicated in cell shape modulation (spreading) and motility. It may participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. FBLIM1 promotes activation of integrins and regulates integrin-mediated cell-cell adhesion. Recombinant human FBLIM1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 43.1 kDa (396aa), confirmed by MALDI-TOF

NCBI Accession: NP_060026

UniProt: Q8WUP2