BSND Protein (AA 54-320) (His tag)

N° du produit ABIN6387238

Détail du produit

Antigène: BSND (Bartter Syndrome, Infantile, with Sensorineural Deafness (Barttin) (BSND))

Type de proteíne: Recombinant

Attributs du protein: AA 54-320

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette BSND protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSCQCYPKI TFVPADSDFQ GILSPKAMGL LENGLAAEMK SPSPQPPYVR LWEEAAYDQS LPDFSHIQMK VMSYSEDHRS LLAPEMGQPK LGTSDGGEGG PGDVQAWMEA AVVIHKGSDE SEGERRLTQS WPGPLACPQG PAPLASFQDD LDMDSSEGSS PNASPHDREE ACSPQQEPQG CRCPLDRFQD FALIDAPTLE DEPQEGQQWE IALPNNWQRY PRTKVEEKEA SDTGGEEPEK EEEDLYYGLP DGAGDLLPDK ELGFEPDTQG

Pureté: > 90 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.15M NaCl, 10 % glycerol, 1  mM DTT

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: BSND (Bartter Syndrome, Infantile, with Sensorineural Deafness (Barttin) (BSND))

Autre désignation: BSND (BSND Produits)

Synonymes: BSND Protein, BART Protein, DFNB73 Protein, Bartter syndrome, infantile, with sensorineural deafness (Barttin) Protein, barttin CLCNK type accessory beta subunit Protein, BSND Protein, Bsnd Protein

Sujet: BSND is an essential beta subunit for CLC chloride channels. These heteromeric channels localize to basolateral membranes of renal tubules and of potassium-secreting epithelia of the inner ear. Mutations in this BSND have been associated with Bartter syndrome with sensorineural deafness. Recombinant human BSND protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 31.7 kDa (290aa) confirmed by MALDI-TOF

NCBI Accession: NP_476517

UniProt: Q8WZ55

Pathways: Sensory Perception of Sound