EXOSC1 Protein (AA 1-195) (His tag)

N° du produit ABIN6387442

Détail du produit

Antigène: EXOSC1 (Exosome Component 1 (EXOSC1))

Type de proteíne: Recombinant

Attributs du protein: AA 1-195

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette EXOSC1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: MGSSHHHHHH SSGLVPRGSH MGSMAPPVRY CIPGERLCNL EEGSPGSGTY TRHGYIFSSL AGCLMKSSEN GALPVVSVVR ETESQLLPDV GAIVTCKVSS INSRFAKVHI LYVGSMPLKN SFRGTIRKED VRATEKDKVE IYKSFRPGDI VLAKVISLGD AQSNYLLTTA ENELGVVVAH SESGIQMVPI SWCEMQCPKT HTKEFRKVAR VQPEFLQT

Pureté: > 90 % by SDS - PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.15M NaCl, 20 % glycerol, 1  mM DTT

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: EXOSC1 (Exosome Component 1 (EXOSC1))

Autre désignation: EXOSC1 (EXOSC1 Produits)

Synonymes: MGC86284 Protein, CGI-108 Protein, CSL4 Protein, Csl4p Protein, SKI4 Protein, Ski4p Protein, hCsl4p Protein, p13 Protein, 2610035C18Rik Protein, 2610104C07Rik Protein, 2610312F07Rik Protein, AI447561 Protein, exosome component 1 Protein, exosome component 1 L homeolog Protein, EXOSC1 Protein, exosc1.L Protein, exosc1 Protein, PTRG_05845 Protein, Exosc1 Protein

Sujet: EXOSC1 is a core component of the exosome. The mammalian exosome is required for rapid degradation of Au rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46. Recombinant human EXOSC1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 23.8 kDa (218aa) confirmed by MALDI-TOF

NCBI Accession: NP_057130

UniProt: Q9Y3B2