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Thymic Stromal Lymphopoietin Protein (TSLP) (AA 29-159) (His tag)

TSLP Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
N° du produit ABIN6387542
  • Antigène Voir toutes Thymic Stromal Lymphopoietin (TSLP) Protéines
    Thymic Stromal Lymphopoietin (TSLP)
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 29-159
    Origine
    • 24
    • 10
    • 5
    • 3
    Humain
    Source
    • 17
    • 16
    • 4
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette Thymic Stromal Lymphopoietin protéine est marqué à la His tag.
    Application
    SDS-PAGE (SDS)
    Séquence
    MGSSHHHHHH SSGLVPRGSH MGSYDFTNCD FEKIKAAYLS TISKDLITYM SGTKSTEFNN TVSCSNRPHC LTEIQSLTFN PTAGCASLAK EMFAMKTKAA LAIWCPGYSE TQINATQAMK KRRKRKVTTN KCLEQVSQLQ GLWRRFNRPL LKQQ
    Pureté
    > 85 % by SDS - PAGE
    Top Product
    Discover our top product TSLP Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Commentaires

    Denatured

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 10 % Glycerol
    Stock
    4 °C,-20 °C,-80 °C
    Stockage commentaire
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Antigène
    Thymic Stromal Lymphopoietin (TSLP)
    Autre désignation
    TSLP (TSLP Produits)
    Synonymes
    TSLP Protein, thymic stromal lymphopoietin Protein, TSLP Protein, Tslp Protein
    Sujet
    TSLP is a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. TSLP is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants. Recombinant human TSLP protein, fused to His-tag at N-terminus, was expressed in E.coli.
    Poids moléculaire
    17.3kDa (154aa)
    NCBI Accession
    NP_149024
    UniProt
    Q969D9
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