Kallikrein 13 Protein (AA 17-277) (His tag)

N° du produit ABIN6387623

Détail du produit

Antigène: Kallikrein 13 (KLK13) (Kallikrein-Related Peptidase 13 (KLK13))

Type de proteíne: Recombinant

Activité biologique: Active

Attributs du protein: AA 17-277

Origine: Humain

Source: Baculovirus infected Insect Cells

Purification/Conjugué: Cette Kallikrein 13 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: GGVSQESSKV LNTNGTSGFL PGGYTCFPHS QPWQAALLVQ GRLLCGGVLV HPKWVLTAAH CLKEGLKVYL GKHALGRVEA GEQVREVVHS IPHPEYRRSP THLNHDHDIM LLELQSPVQL TGYIQTLPLS HNNRLTPGTT CRVSGWGTTT SPQVNYPKTL QCANIQLRSD EECRQVYPGK ITDNMLCAGT KEGGKDSCEG DSGGPLVCNR TLYGIVSWGD FPCGQPDRPG VYTRVSRYVL WIRETIRKYE TQQQKWLKGP QHHHHHH

Pureté: > 90 % by SDS - PAGE

niveau d'endotoxine: < 1.0 EU per 1 microgram of protein (determined by LAL method)

Biological Activity Comment: Specific activity is > 8,000 pmol/min/ug. One unit will hydrolyze 1.0 pmole of BAEE to Na-Benzoyl-L-arginine per minute at pH8.0 at 25C.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Bioactivity Validated

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: Kallikrein 13 (KLK13) (Kallikrein-Related Peptidase 13 (KLK13))

Autre désignation: KLK13 (KLK13 Produits)

Synonymes: KLK-L4 Protein, KLKL4 Protein, Egfbp-2 Protein, mGk-13 Protein, kallikrein related peptidase 13 Protein, kallikrein related-peptidase 13 Protein, KLK13 Protein, Klk13 Protein

Sujet: KLK13, also known as kallikrein-13, belongs to Kallikrein subfamily. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK13 is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Expression of this gene is regulated by steroid hormones and may be useful as a marker for breast cancer. An additional transcript variant has been identified, but its full length sequence has not been determined. Recombinant human KLK13, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Poids moléculaire: 29.7kDa (267aa) 28-40KDa (SDS-PAGE under reducing conditions.)

NCBI Accession: NP_056411

UniProt: Q9UKR3

Pathways: Système du Complément