NAGA Protein (AA 18-411) (His tag)

N° du produit ABIN6387829

Détail du produit

Antigène: NAGA (N-Acetylgalactosaminidase, alpha (NAGA))

Type de proteíne: Recombinant

Attributs du protein: AA 18-411

Origine: Humain

Source: Baculovirus infected Insect Cells

Purification/Conjugué: Cette NAGA protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: LDNGLLQTPP MGWLAWERFR CNINCDEDPK NCISEQLFME MADRMAQDGW RDMGYTYLNI DDCWIGGRDA SGRLMPDPKR FPHGIPFLAD YVHSLGLKLG IYADMGNFTC MGYPGTTLDK VVQDAQTFAE WKVDMLKLDG CFSTPEERAQ GYPKMAAALN ATGRPIAFSC SWPAYEGGLP PRVNYSLLAD ICNLWRNYDD IQDSWWSVLS ILNWFVEHQD ILQPVAGPGH WNDPDMLLIG NFGLSLEQSR AQMALWTVLA APLLMSTDLR TISAQNMDIL QNPLMIKINQ DPLGIQGRRI HKEKSLIEVY MRPLSNKASA LVFFSCRTDM PYRYHSSLGQ LNFTGSVIYE AQDVYSGDII SGLRDETNFT VIINPSGVVM WYLYPIKNLE MSQQHHHHHH

Pureté: > 90 % by SDS - PAGE.

niveau d'endotoxine: < 1.0 EU per 1 microgram of protein (determined by LAL method)

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: NAGA (N-Acetylgalactosaminidase, alpha (NAGA))

Autre désignation: NAGA (NAGA Produits)

Synonymes: D22S674 Protein, GALB Protein, alpha-N-acetylgalactosaminidase Protein, N-acetyl galactosaminidase, alpha Protein, Naga Protein, NAGA Protein

Sujet: NAGA, also known as alpha-N-acetylgalactosaminidase, is a lysosomal exoglycosidase that cleaves terminal alpha-N-acetylgalactosamine residues from glycopeptides and glycolipids. It is hardly expected to cause an allergic reaction in Fabry disease patients. It is highly promising as a new and safe enzyme for ERT for Fabry disease. Recombinant human NAGA, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Poids moléculaire: 45.5kDa (400aa) 40-57kDa (SDS-PAGE under reducing conditions

NCBI Accession: NP_000253

UniProt: P17050