BIN2 Protein (AA 1-597) (His tag)

N° du produit ABIN6388106

Détail du produit

Antigène: BIN2 (Bridging Integrator 2 (BIN2))

Type de proteíne: Recombinant

Attributs du protein: AA 1-597

Origine: Humain

Source: Baculovirus infected Insect Cells

Purification/Conjugué: Cette BIN2 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: ADPMRGMPGA RTSSSGASEN HRARGQGGGP QGVGRMAEGK AGGAAGLFAK QVQKKFSRAQ EKVLQKLGKA VETKDERFEQ SASNFYQQQA EGHKLYKDLK NFLSAVKVMH ESSKRVSETL QEIYSSEWDG HEELKAIVWN NDLLWEDYEE KLADQAVRTM EIYVAQFSEI KERIAKRGRK LVDYDSARHH LEAVQNAKKK DEAKTAKAEE EFNKAQTVFE DLNQELLEEL PILYNSRIGC YVTIFQNISN LRDVFYREMS KLNHNLYEVM SKLEKQHSNK VFVVKGLSSS SRRSLVISPP VRTATVSSPL TSPTSPSTLS LKSESESVSA TEDLAPDAAQ GEDNSEIKEL LEEEEIEKEG SEASSSEEDE PLPACNGPAQ AQPSPTTERA KSQEEVLPSS TTPSPGGALS PSGQPSSSAT EVVLRTRTAS EGSEQPKKRA SIQRTSAPPS RPPPPRATAS PRPSSGNIPS SPTASGGGSP TSPRASLGTG TASPRTSLEV SPNPEPPEKP VRTPEAKENE NIHNQNPEEL CTSPTLMTSQ VASEPGEAKK MEDKEKDNKL ISANSSEGQD QLQVSMVPEN NNLTAPEPQE EVSTSENPQL HHHHHH

Pureté: > 80 % by SDS - PAGE

niveau d'endotoxine: < 1.0 EU per 1ug of protein (determined by LAL method)

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 20 % glycerol, 1  mM DTT, 0.1  mM PMSF.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: BIN2 (Bridging Integrator 2 (BIN2))

Autre désignation: BIN2 (BIN2 Produits)

Synonymes: BRAP-1 Protein, BIN2 Protein, bin2l Protein, wu:fi05e01 Protein, zgc:55758 Protein, bridging integrator 2 Protein, bridging integrator 2b Protein, BIN2 Protein, Bin2 Protein, bin2b Protein

Sujet: BIN2, also known as bridging integrator 2 isoform1, is a cytoplasmic protein. It contains one BAR domain and Interacts with BIN1. This protein is highly expressed in some hematopoietic tissues, including peripheral blood, thymus, colon and placenta. It Promotes cell motility and migration, probably via its interaction with the cell membrane and with podosome proteins that mediate interaction with the cytoskeleton and also modulates membrane curvature and mediates membrane tubulation. Recombinant human BIN2 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Poids moléculaire: 66.1kDa (606aa) 70-100KDa (SDS-PAGE under reducing conditions.)

NCBI Accession: NP_057377

UniProt: Q9UBW5