IL7R Protein (AA 21-239) (hIgG-His-tag)

N° du produit ABIN6388135

Détail du produit

Antigène: IL7R (Interleukin 7 Receptor (IL7R))

Type de proteíne: Recombinant

Attributs du protein: AA 21-239

Origine: Humain

Source: Baculovirus infected Insect Cells

Purification/Conjugué: Cette IL7R protéine est marqué à la hIgG-His-tag.

Application: SDS-PAGE (SDS)

Séquence: ADLESGYAQN GDLEDAELDD YSFSCYSQLE VNGSQHSLTC AFEDPDVNIT NLEFEICGAL VEVKCLNFRK LQEIYFIETK KFLLIGKSNI CVKVGEKSLT CKKIDLTTIV KPEAPFDLSV VYREGANDFV VTFNTSHLQK KYVKVLMHDV AYRQEKDENK WTHVNLSSTK LTLLQRKLQP AAMYEIKVRS IPDHYFKGFW SEWSPSYYFR TPEINNSSGE MDLEPKSCDK THTCPPCPAP ELLGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VKFNWYVDGV EVHNAKTKPR EEQYNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKALPAPI EKTISKAKGQ PREPQVYTLP PSRDELTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPVLDSDG SFFLYSKLTV DKSRWQQGNV FSCSVMHEAL HNHYTQKSLS LSPGKHHHHH H

Pureté: > 90 % by SDS - PAGE

niveau d'endotoxine: < 1.0 EU per 1ug of protein (determined by LAL method)

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: IL7R (Interleukin 7 Receptor (IL7R))

Autre désignation: IL7R (IL7R Produits)

Synonymes: IL7R Protein, CD127 Protein, IL-7Ralpha Protein, CDW127 Protein, IL-7R-alpha Protein, IL7RA Protein, ILRA Protein, IL-7RA Protein, interleukin 7 receptor Protein, IL7R Protein, Il7r Protein

Sujet: IL7R, also known as interleukin-7 receptor, is a hematopoietin receptor superfamily member. It plays important role in lymphocyte differentiation, proliferation, multiple sclerosis, and survival. This protein signaling is essential for T-cell development and regulation of native and memory T-cell homeostasis. Also, it is critically required for the proper development and function of lymphoid cells. Recombinant human IL7R, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Poids moléculaire: 52.5kDa (461aa) 50-70kDa (SDS-PAGE under reducing conditions)

NCBI Accession: NP_002176

UniProt: P16871

Pathways: Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size