CD52 Protein (CD52) (AA 21-248) (hIgG-His-tag)

N° du produit ABIN6388179

Détail du produit

Antigène: CD52

Type de proteíne: Recombinant

Attributs du protein: AA 21-248

Origine: Humain

Source: Baculovirus infected Insect Cells

Purification/Conjugué: Cette CD52 protéine est marqué à la hIgG-His-tag.

Application: SDS-PAGE (SDS)

Pureté: > 90 % by SDS - PAGE

niveau d'endotoxine: < 1.0 EU per 1ug of protein (determined by LAL method)

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: CD52

Autre désignation: CD52 (CD52 Produits)

Synonymes: CD52 Protein, AI463198 Protein, B7 Protein, B7-Ag Protein, CAMPATH-1 Protein, CLS1 Protein, MB7 Protein, CDW52 Protein, CE5 Protein, CD52 molecule Protein, CD52 antigen Protein, CD52 Protein, Cd52 Protein

Sujet: MBL2, also known as mannose-binding protein C, belongs to the class of collectins in the C-type lectin superfamily. It is a lectin that is instrumental in innate immunity via the lectin pathway. It recognizes carbohydrate patterns, found on the surface of a large number of pathogenic micro-organisms, including bacteria, viruses, protozoa and fungi. It It binds senescent and apoptotic cells and enhances engulfment of whole, intact apoptotic cells, as well as cell debris by phagocytes. This protein has recently been found to play a role in development of type 1 diabetes and gestational diabetes mellitus. Also, mutant MBL2 haplotypes have been linked to disease progression and response to therapy in HCV infection. Recombinant human MBL2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Poids moléculaire: 25.1kDa (237aa) 28-40kDa (SDS-PAGE under reducing conditions)

NCBI Accession: NP_000233

UniProt: P11226