M-CSF/CSF1 Protein (AA 33-190) (His tag)

N° du produit ABIN666654

Détail du produit

Antigène: M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

Type de proteíne: Recombinant

Attributs du protein: AA 33-190

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette M-CSF/CSF1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: MCSF, 33-190 aa, Human, His-tagged, E.coli

Pureté: > 90 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl buffer (pH8.0), 2mM DTT, 10% glycerol

Stock: 4 °C

Détail du antigène

Antigène: M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

Autre désignation: MCSF (CSF1 Produits)

Synonymes: CSF-1 Protein, MCSF Protein, C87615 Protein, Csfm Protein, op Protein, csf1-1 Protein, zgc:172186 Protein, CSF1 Protein, csf1-2 Protein, zgc:158436 Protein, colony stimulating factor 1 Protein, colony stimulating factor 1 (macrophage) Protein, colony stimulating factor 1a (macrophage) Protein, macrophage colony-stimulating factor 1 Protein, macrophage colony stimulating factor Protein, colony stimulating factor 1b (macrophage) Protein, CSF1 Protein, Csf1 Protein, csf1a Protein, LOC396599 Protein, LOC100860895 Protein, csf1b Protein

Sujet: Macrophage colony stimulating factor (M-CSF), as known as CSF-1, one of the hematopoietic growth factors that regulate the growth and differentiation of blood cells. This protein is produced by monocytes, granulocytes, endothelial cells, and fibroblasts. It stimulates the formation of macrophage colonies, enhances antibody-dependent, cell-mediated cytotoxicity by monocytes and macrophages, and inhibits bone resorption by osteoclasts. Recombinant human M-CSF, fused to His-tag at N-terminus, was expressed as insoluble protein aggregate in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. . Synonyms: CSF1 , Macrophage colony stimulating factor Colony stimulating factor 1, CSF 1, Lanimostim, M CSF, Macrophage Colony Stimulating Factor 1, MCSF, MGC31930. NCBI no.: NP_757351

Poids moléculaire: 20.7 kDa (179aa), confirmed by MALDI-TOF.

Pathways: Signalisation RTK