Complexin 1 Protein (CPLX1) (AA 1-134) (His tag)

N° du produit ABIN666720

Détail du produit

Antigène: Complexin 1 (CPLX1)

Type de proteíne: Recombinant

Attributs du protein: AA 1-134

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette Complexin 1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: Complexin1, 1-134aa, Human, His tagged, Recombinant, E.coli

Pureté: > 90 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Stock: 4 °C

Détail du antigène

Antigène: Complexin 1 (CPLX1)

Autre désignation: Complexin1 (CPLX1 Produits)

Synonymes: MGC84299 Protein, CPLX1 Protein, CPX-I Protein, CPX1 Protein, 921-S Protein, complexin 1 L homeolog Protein, complexin 1 Protein, cplx1.L Protein, CPLX1 Protein, cplx1 Protein, Cplx1 Protein

Sujet: Complexin1 belongs to a family of SNARE complex binding proteins that were suggested to be either facilitators or inhibitors of vesicle exocytosis. Complexin 1 exhibits reduced Ca2+-triggered fast neurotransmitter release at hippocampal glutamatergic synapses, indicating that this protein is a positive regulator of transmitter release. In contrast, it inhibits SNARE-mediated liposome and cell fusions in vitro, which lead to the hypothesis that it acts as fusion clamps of synaptic exocytosis. Recombinant Complexin 1 protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: CPXL1, CPX1, Synaphin-2, Complexin 1, Complexin I, CPX1, Synaphin 2,. NCBI no.: NP_006642

Poids moléculaire: 17.1 kDa (154 aa), confirmed by MALDI-TOF. (Molecular weight on SDS-PAGE will appear higher)

Pathways: Hormone Transport, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport