GDF5 Protein (AA 382-501) (His tag)

N° du produit ABIN666773

Détail du produit

Antigène: GDF5 (Growth Differentiation Factor 5 (GDF5))

Type de proteíne: Recombinant

Attributs du protein: AA 382-501

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette GDF5 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: GDF-5, 382-501aa, Human, His-tagged, Recombinant, E.coli

Pureté: > 95 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 10 mM Sodium citrate pH 3.5, 10% glycerol

Stock: 4 °C

Détail du antigène

Antigène: GDF5 (Growth Differentiation Factor 5 (GDF5))

Autre désignation: GDF-5 (GDF5 Produits)

Synonymes: CDMP1 Protein, gdf Protein, gdf-5 Protein, GDF5 Protein, BDA1C Protein, BMP14 Protein, LAP4 Protein, OS5 Protein, SYM1B Protein, SYNS2 Protein, Cdmp-1 Protein, bp Protein, brp Protein, Cdmp1 Protein, growth differentiation factor 5 L homeolog Protein, growth differentiation factor 5 Protein, gdf5.L Protein, GDF5 Protein, Gdf5 Protein

Sujet: Growth differentiation factor 5(GDF-5) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This protein plays a role in chondrogenesis and chondrocyte metabolism, tendon and ligament tissue formation, and bone repair. It also increases the survival of neurones that respond to a neurotransmitter called dopamine, and is a potential therapeutic molecule associated with Parkinson's disease. GDF-5, fused to His-tag at N-terminus, was expressed as insoluble protein aggregate in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. Synonyms: Growth differentiation factor 5, BMP14, CDMP1, LAP4, OS5, SYNS2, Growth differentiation factor 5 Cartilage derived morphogenetic protein 1,. NCBI no.: NP_000548

Poids moléculaire: 15.8 kDa (141aa), confirmed by MALDI-TOF.