OAS1 Protein (AA 1-364) (His tag)

N° du produit ABIN666789

Détail du produit

Antigène: OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))

Type de proteíne: Recombinant

Attributs du protein: AA 1-364

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette OAS1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: OAS1, 1-364 aa, Human, His-tagged, Recombinant, E.coli

Pureté: > 95 % by SDS-PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol and 1mM DTT.

Stock: 4 °C

Détail du antigène

Antigène: OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))

Autre désignation: OAS1 (OAS1 Produits)

Synonymes: OAS1 Protein, IFI-4 Protein, OIAS Protein, OIASI Protein, L3 Protein, Pp2a2 Protein, 2',5'-oligoadenylate synthetase 1 Protein, 2'-5'-oligoadenylate synthetase 1 Protein, 2'-5' oligoadenylate synthetase 1A Protein, protein phosphatase 2 catalytic subunit beta Protein, OAS1 Protein, Oas1a Protein, Ppp2cb Protein, Oas1 Protein

Sujet: OAS1 is an enzyme included in the 2’,5’-oligoadenylate synthase family. This enzyme is induced by interferons and uses adenosine triphosphate in 2’-specific nucleotidyl transfer reactions to synthesize 2’,5’-oligoadenylates(2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. OAS1 may play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. Recombinant OAS1 protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: IFI-4, OIAS, OIASI, 2’,5’-oligoadenylate synthetase 1, isoform2 (2 5')oligo(A) synthetase 1, 2' 5' oligo A synthetase 1, 2 5 Oligoadenylate Synthetase 1, 2 5A synthetase 1, 2' 5' oligoadenylate synthetase 1, 2' 5' oligoisoadenylate synthetase 1, 2'5' oligoadenylate synthetase 1, 2'5' oligoisoadenylate synthetase 1, p46/p42 OAS, 2'5' oligo A synthetase 1, E18/E16, IFI 4, IFI4, OAS 1,. NCBI no.: NP_002525

Poids moléculaire: 43.9 kDa (384aa), confirmed by MALDI-TOF.

Pathways: Hepatitis C