SMAD3 Protein (AA 1-425) (His tag)

N° du produit ABIN666909

Détail du produit

Antigène: SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))

Type de proteíne: Recombinant

Attributs du protein: AA 1-425

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette SMAD3 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: SMAD3, 1-425 aa, Human, His-tag, E.coli

Pureté: > 90 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl and 1 mM DTT

Stock: 4 °C

Détail du antigène

Antigène: SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))

Autre désignation: SMAD3 (SMAD3 Produits)

Synonymes: HSPC193 Protein, HsT17436 Protein, JV15-2 Protein, LDS1C Protein, LDS3 Protein, MADH3 Protein, madh3 Protein, madh3a Protein, smad3 Protein, wu:fa99e03 Protein, XSmad3 Protein, XenMLP Protein, Xmad3 Protein, madh3-A Protein, Madh3 Protein, AU022421 Protein, Smad 3 Protein, mad3 Protein, madh3b Protein, zgc:92234 Protein, SMAD family member 3 Protein, SMAD family member 3a Protein, SMAD family member 3 L homeolog Protein, SMAD family member 3b Protein, SMAD3 Protein, smad3a Protein, smad3.L Protein, Smad3 Protein, smad3b Protein

Sujet: SMAD3, also known as mothers against decapentaplegic homolog 3, belongs to the SMAD family of proteins that mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. Small moleucule inhibitors of Smad3 may have tremendous clinical potential in the treatment of pathological fibrotic diseases. Recombinant SMAD3 protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: HSPC193, HsT17436, JV15-2, MADH3, Mothers against decapentaplegic homolog 3 DKFZP586N0721, DKFZp686J10186, hMAD 3, hSMAD3, MAD (mothers against decapentaplegic Drosophila) homolog 3, HST17436, JV15 2, JV152, MAD3, MADH 3, MGC60396, Mothers against DPP homolog 3, SMA and MAD related protein 3, SMAD, SMAD 3, SMAD3,. NCBI no.: NP_005893

Poids moléculaire: 50.2 kDa (445aa), confirmed by MALDI-TOF.

Pathways: Cycle Cellulaire, Chromatin Binding, Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity, Autophagy