CRNN Protein (AA 1-495) (His tag)

N° du produit ABIN666956

Détail du produit

Antigène: CRNN (Cornulin (CRNN))

Type de proteíne: Recombinant

Attributs du protein: AA 1-495

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette CRNN protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: CRNN, 1-495aa, Human, His tag, E.coli

Pureté: > 85 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol

Stock: 4 °C

Détail du antigène

Antigène: CRNN (Cornulin (CRNN))

Autre désignation: CRNN (CRNN Produits)

Synonymes: C1orf10 Protein, DRC1 Protein, PDRC1 Protein, SEP53 Protein, RGD1311778 Protein, Gm1015 Protein, cornulin Protein, CRNN Protein, Crnn Protein, LOC100359146 Protein

Sujet: CRNN is a member of the 'fused gene' family of proteins, which contain N-terminus EF-hand domains and multiple tandem peptide repeats. It contains two EF-hand Ca2+ binding domains in its N-terminus and two glutamine- and threonine-rich 60 amino acid repeats in its C-terminus. This protein, also Known as Survival factor that participates in the clonogenicity of squamous esophageal epithelium cell lines, attenuates deoxycholic acid (DCA)-induced apoptotic cell death and release of calcium. When overexpressed in oral squamous carcinom cell lines, regulates negatively cell proliferation by the induction of G1 arrest. Recombinant CRNN protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: DRC1, PDRC1, SEP53, Cornulin 53 kDa putative calcium binding protein, 53 kDa squamous epithelial induced stress protein, 58 kDa heat shock protein, C1orf10, Squamous epithelial heat shock protein 53, Tumor related protein. NCBI no.: AAH30807

Poids moléculaire: 55.7 kDa (515aa)