TXN Protein (AA 1-105) (His tag)

N° du produit ABIN666978

Détail du produit

Antigène: TXN (Thioredoxin (TXN))

Type de proteíne: Recombinant

Attributs du protein: AA 1-105

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette TXN protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: TXN, 1-105 aa, Human, His-tagged, Recombinant, E.coli

Pureté: > 95 % by SDS-PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In Phosphate Buffered Saline pH7.4

Stock: 4 °C

Détail du antigène

Antigène: TXN (Thioredoxin (TXN))

Autre désignation: TXN (TXN Produits)

Synonymes: TRDX Protein, TRX Protein, TRX1 Protein, ADF Protein, AW550880 Protein, Trx1 Protein, Txn Protein, trx Protein, TXN Protein, SCM1.18 Protein, trxA3 Protein, thioredoxin Protein, TR-1 Protein, Trx-1 Protein, thioredoxin Protein, thioredoxin 1 Protein, thioredoxin L homeolog Protein, similar to 44RRORF109c hypothetical protein; similar to bacterial thioredoxin (SwissProt P06544) Protein, thioredoxin pseudogene Protein, cytosolic thioredoxin Trx1 Protein, TXN Protein, Txn1 Protein, txn.L Protein, txn Protein, trx Protein, SCO0885 Protein, PHG25ORF099c Protein, LOC100349046 Protein, Txn Protein, trx1 Protein

Sujet: SQSTM1 is an adapter protein which binds ubiquitin and regulates signaling cascades through ubiquitination. It may regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1 and play a role in titin/TTN downstream signaling in muscle cells. This protein also may be involved in cell differentiation, apoptosis, immune response and regulation of K+ channels. Mutations in the ubiquitin-associated (UBA) domain of the sequestosome 1 protein commonly cause Paget’s disease since the UBA is necessary for aggregate sequestration and cell survival. Recombinant SQSTM1 protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: TRX, TRX1, Thioredoxin JW0871, ECK0879, Thioredoxin reductase, FAD/NAD(P)-binding, TRXR. NCBI no.: NP_003320

Poids moléculaire: 13.9 kDa (125aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Pathways: Carbohydrate Homeostasis, Cell RedoxHomeostasis