Lymphotactin, also known as XCL1, is member of gamma or C subfamily of chemokines. It is found in high levels in spleen, thymus, intestine and peripheral blood leukocytes, and at lower levels in lung, prostate gland and ovary. The expression of lymphotactin is restricted to activated T cells such as activated CD8+ T cells and other calss IMHC restricted T cells. Since lymphotactin is produced by lymphocytes and acts on lymphocytes, it is speculated that it is a messenger in T cell chemoattraction. Recombinant human XCL1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: XCL1, ATAC, LPTN, LTN, SCM-1, SCM-1a, SCM1, SCYC1, Chemokine (C motif) ligand 1, Lymphotactin/XCL1, Chemokine (C motif) ligand 1 C motif chemokine 1, SCM 1 alpha, SCM1, SCYC1, Chemokine C Motif Ligand 1, Small inducible cytokine C1, Small Inducible Cytokine Subfamily C Member 1, XC chemokine ligand 1, XCL1. NCBI no.: NP_002986
Poids moléculaire
12.5 kDa (114aa), confirmed by MALDI-TOF. (Molecular weight on SDS-PAGE will appear higher)