GUK1 Protein (AA 1-197) (His tag)

N° du produit ABIN667195

Détail du produit

Antigène: GUK1 (Guanylate Kinase 1 (GUK1))

Type de proteíne: Recombinant

Attributs du protein: AA 1-197

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette GUK1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: GUK1, 1-197aa, Human, His tag, E.coli

Pureté: > 90 % by SDS – PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT, 0.1M NaCl.

Stock: 4 °C

Détail du antigène

Antigène: GUK1 (Guanylate Kinase 1 (GUK1))

Autre désignation: GUK1 (GUK1 Produits)

Synonymes: GMK Protein, AA409738 Protein, AL033299 Protein, AL033300 Protein, AV026611 Protein, Gmk Protein, Guk-1 Protein, guk1 Protein, zgc:73128 Protein, zgc:73217 Protein, gmk Protein, GUK1 Protein, AGK1 Protein, T11A7.23 Protein, guanylate kinase 1 Protein, DDBDRAFT_0215291 Protein, DDBDRAFT_0230100 Protein, DDB_0215291 Protein, DDB_0230100 Protein, sb:cb295 Protein, zgc:86776 Protein, guanylate kinase 1 Protein, guanylate kinase (GUK1) Protein, guanylate kinase Protein, guanylate kinase 1b Protein, guanylate kinase 1 L homeolog Protein, guanylate kinase 1a Protein, GUK1 Protein, Guk1 Protein, guk1b Protein, guk1 Protein, guk1.L Protein, GK-1 Protein, gmk Protein, gmkA Protein, Mrub_2093 Protein, Arnit_0783 Protein, Ndas_3097 Protein, Mesil_1319 Protein, Slip_0854 Protein, Olsu_0986 Protein, Acear_1451 Protein, AOR_1_2886174 Protein, guk1a Protein

Sujet: GUK1, also known as GMK, belongs to the guanylate kinase family. This protein exists as a monomer that catalyzes the ATP-dependent conversion of GMP to GDP, thereby playing an essential role in the recycling of GMP. Via its catalytic activity, GUK1 is thought to participate in regulating the supply of guanine nucleotides to signal transduction pathways. Overexpression of GUK1 is associated with pituitary adenocarcinomas, suggesting that GUK1 is involved in tumorigenesis. Recombinant human GUK1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: GMK, GMP kinase, Guanylate kinase. NCBI no.: NP_000849

Poids moléculaire: 23.9 kDa (217aa), confirmed by MALDI-TOF

Pathways: Nucleotide Phosphorylation, ER-Nucleus Signaling, Ribonucleoside Biosynthetic Process