CDA Protein (AA 1-146) (His tag)

N° du produit ABIN667230

Détail du produit

Antigène: CDA (Cytidine Deaminase (CDA))

Type de proteíne: Recombinant

Attributs du protein: AA 1-146

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette CDA protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: CDA, 1-146aa, Human, His tag, E.coli

Pureté: > 90 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 1 mM DTT, 2 mM EDTA, 100 mM NaCl, 40% Glycerol

Stock: 4 °C

Détail du antigène

Antigène: CDA (Cytidine Deaminase (CDA))

Autre désignation: CDA (CDA Produits)

Synonymes: CDA Protein, cda Protein, zgc:77948 Protein, DDBDRAFT_0188181 Protein, DDBDRAFT_0230205 Protein, DDB_0188181 Protein, DDB_0230205 Protein, CDD Protein, 2210401N16Rik Protein, cytidine deaminase Protein, cytidine aminohydrolase; CDA Protein, cytidine deaminase b Protein, Cytidine deaminase Protein, cytidine deaminase Cdd Protein, CDA Protein, cda Protein, VNG_RS03500 Protein, OE_RS03485 Protein, CDD1 Protein, cdd Protein, cdab Protein, cdd-1 Protein, cdd-2 Protein, CNC04940 Protein, Tb09.160.1680 Protein, Cda Protein

Sujet: CDA (Cytidine deaminase) is an enzyme that scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. This protein is one of several deaminases responsible for maintaining the cellular pyrimidine pool. The protein also catalyzes the deamination of chemotherapeutic cytosine nucleoside analogs such as Ara-C and 5-azacytidine, which results in the loss of their cytotoxic and antitumor function. It can form homotetramers and is mainly expressed in granulocytes. Recombinant human CDA protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: CDD, Cytidine aminohydrolase, Cytosine nucleoside deaminase, Cytidine deaminase. NCBI no.: AAH54036

Poids moléculaire: 18.3 kDa(166aa), confirmed by MALDI-TOF