BLMH Protein (AA 1-455) (His tag)

N° du produit ABIN667250

Détail du produit

Antigène: BLMH (Bleomycin Hydrolase (BLMH))

Type de proteíne: Recombinant

Attributs du protein: AA 1-455

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette BLMH protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: BLMH, 1-455aa, Human, His tag, E.coli

Pureté: > 90 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 10% Glycerol

Stock: 4 °C

Détail du antigène

Antigène: BLMH (Bleomycin Hydrolase (BLMH))

Autre désignation: BLMH (BLMH Produits)

Synonymes: AI035728 Protein, Bh Protein, Bmh Protein, wu:fb13c01 Protein, zgc:66261 Protein, bh Protein, bmh Protein, BH Protein, BMH Protein, bleomycin hydrolase Protein, Bleomycin hydrolase Protein, bleomycin hydrolase S homeolog Protein, BLMH Protein, pepC Protein, LOC5569945 Protein, Apre_0140 Protein, Apar_0899 Protein, Smon_1289 Protein, Kfla_1242 Protein, Snas_3912 Protein, BLJ_1941 Protein, Olsu_1085 Protein, PGTDC60_0106 Protein, Blmh Protein, blmh Protein, blmh.S Protein

Sujet: BLMH is a member of the papain superfamily of the cysteine protease and the peptidase C1 family. It is a cytoplasmic cysteinepeptidase commonly found as a homohexamer. The normal physiological role of BLMH is unknown, but it protects normal and malignant cells from the glycopeptide antitumor drug BLM. It catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxyamide bond of its B-aminoalaninamide moiety and also shows general aminopeptidase activity. Recombinant human BLMH protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Bleomycin hydrolase, BH, BMH. NCBI no.: NP_000377

Poids moléculaire: 54.7 kDa(475aa), confirmed by MALDI-TOF