RAB5B Protein (AA 1-215) (His tag)

N° du produit ABIN667307

Détail du produit

Antigène: RAB5B (RAB5B, Member RAS Oncogene Family (RAB5B))

Type de proteíne: Recombinant

Attributs du protein: AA 1-215

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette RAB5B protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: RAB5B, 1-215aa, Human, His tag, E.coli

Pureté: > 90 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 0.2M NaCl

Stock: 4 °C

Détail du antigène

Antigène: RAB5B (RAB5B, Member RAS Oncogene Family (RAB5B))

Autre désignation: RAB5B (RAB5B Produits)

Synonymes: zgc:76978 Protein, C030027M18Rik Protein, RAB5B, member RAS oncogene family Protein, RAB5B, member RAS oncogene family L homeolog Protein, rab5b Protein, LOC613071 Protein, RAB5B Protein, Rab5b Protein, rab5b.L Protein

Sujet: Ras-related protein Rab-5B, also known as RAB5B, is a member of the Rab family of small (monomeric) G proteins. RAB5B is involved in endocytosis and recycling of cell surface molecules. It interacts with RIN2 and RIN3, which regulate its function, possibly by acting as GEFs. Knockdown of RAB5B abolished group I metabotropic glutamate receptor (mGluR)-mediated neuroprotection. Recombinant human RAB5B protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Ras-related protein Rab-5B, Rab 5b, Rab5 b, RAB5B member RAS oncogene family, Ras related protein Rab 5B. NCBI no.: NP_002859

Poids moléculaire: 26.1 kDa (238aa), confirmed by MALDI-TOF