eIF4EBP2 Protein (AA 1-120) (His tag)

N° du produit ABIN667385

Détail du produit

Antigène: eIF4EBP2 (EIF4EBP2) (Eukaryotic Translation Initiation Factor 4E Binding Protein 2 (EIF4EBP2))

Type de proteíne: Recombinant

Attributs du protein: AA 1-120

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette eIF4EBP2 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: EIF4EBP2, 1-120aa, Human, His tag, E.coli

Pureté: > 85 % by SDS – PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT, 0.1M NaCl.

Stock: 4 °C

Détail du antigène

Antigène: eIF4EBP2 (EIF4EBP2) (Eukaryotic Translation Initiation Factor 4E Binding Protein 2 (EIF4EBP2))

Autre désignation: EIF4EBP2 (EIF4EBP2 Produits)

Synonymes: 4ebp2 Protein, MGC75579 Protein, wu:fa55e11 Protein, wu:fp45e09 Protein, MGC78987 Protein, EIF4EBP2 Protein, eIF-4E Protein, Tb06.28P18.1010 Protein, 4EBP2 Protein, PHASII Protein, 2810011I19Rik Protein, 4E-BP2 Protein, AA792569 Protein, BC010348 Protein, PHAS-II Protein, eukaryotic translation initiation factor 4E binding protein 2 Protein, eukaryotic translation initiation factor 4E binding protein 2 L homeolog Protein, eukaryotic initiation factor 4E Protein, eukaryotic translation initiation factor 4E Protein, putative eukaryotic translation initiation factor 4e Protein, eif4ebp2 Protein, Eif4ebp2 Protein, eif4ebp2.L Protein, EIF4EBP2 Protein, eIF-4E Protein, Tb927.6.1870 Protein, LMJF_30_0450 Protein

Sujet: EIF4EBP2 is a member of the eukaryotic translation initiation factor 4E binding protein family. This protein binds eIF4E and inhibits translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. It mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase pathway. Regulation of this protein has been implicated in cell proliferation, cell differentiation and viral infection. Recombinant human EIF4EBP2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Eukaryotic translation initiation factor 4E binding protein 2, 4EBP2, PHASII. NCBI no.: NP_004087

Poids moléculaire: 15.1 kDa (140aa) confirmed by MALDI-TOF